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| Santos,E.J.F.; Hortegal,E.V.; Serra,H.O.; Lages,J.S.; Salgado-Filho,N.; dos Santos,A.M.. |
| Anemia is an inevitable complication of hemodialysis, and the primary cause is erythropoietin deficiency. After diagnosis, treatment begins with an erythropoiesis-stimulating agent (ESA). However, some patients remain anemic even after receiving this medication. This study aimed to investigate the factors associated with resistance to recombinant human erythropoietin therapy with epoetin alfa (αEPO). We performed a prospective, longitudinal study of hemodialysis patients receiving treatment with αEPO at our reference hospital from July 2015 to June 2016. Clinical data was collected, and the response to αEPO treatment was evaluated using the erythropoietin resistance index (ERI). The ERI was defined as the weekly weight-adjusted αEPO dose (U/kg per... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Epoetin alfa; Drug resistance; Renal insufficiency; Chronic disease; Renal dialysis. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000700603 |
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| Takemoto,Angélica Yukari; Okubo,Patrícia; Saito,Patricia Keiko; Yamakawa,Roger Haruki; Watanabe,Maria Angélica Ehara; Veríssimo da Silva Junior,Waldir; Borelli,Sueli Donizete; Bedendo,João. |
| Patients who undergo dialysis treatment or a renal transplant have a high risk of blood-borne viral infections, including the Torque teno virus (TTV). This study identified the presence of TTV and its genome groups in blood samples from 118 patients in dialysis and 50 renal-transplant recipients. The research was conducted in a hospital in the city of Maringá, state of Paraná. The viral DNA, obtained from whole blood, was identified by using two nested Polymerase Chain Reactions (PCR). The frequencies of TTV were 17% and 36% in dialysis patients using the methodology proposed by Nishizawa et al. (1997) and Devalle and Niel (2004), respectively, and 10% and 54% among renal-transplant patients. There was no statistically significant association between the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Torque teno virus; Renal dialysis; Kidney transplant; Infection. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100307 |
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